Evidence synthesis, reimagined.
ActiveTLR helps pharma, biotech, and CRO evidence teams go from a clinical question to a transparent, PRISMA-ready synthesis in hours — without trading away the rigour a regulator expects.
To accelerate evidence-based decisions with targeted literature reviews that are fast, transparent, and audit-ready — so experts spend their time on judgement, not manual triage.
A world where research synthesis is seamless, reliable, and reproducible — driven by technology that puts precision and integrity first.
Driven by research, defined by integrity.
Targeted literature reviews are the backbone of regulatory, HEOR, and medical-affairs evidence. Yet most of the work is still done by hand: crafting Boolean strings, de-duplicating exports, and screening thousands of abstracts one by one. It is slow, hard to reproduce, and unforgiving of a single missed paper.
We thought that process deserved better tooling — not a shortcut that hides the method, but software that performs each step in the open and hands the reviewer a clear, auditable trail. That belief is what ActiveTLR is built on.
The platform compresses the manual stages of a review while keeping a human in control at every decision point, so teams can move faster and still stand behind every output.
Principles behind the platform
The same standards we’d want from any evidence we put our name to.
Transparency
Every search strategy, screening decision, and count is shown with its rationale. Nothing happens in a black box you can't inspect.
Reproducibility
Methods are captured end to end - from the framework to the PRISMA flow - so any reviewer can retrace and re-run exactly what was done.
Human-in-the-loop
AI does the heavy lifting; people stay in control. Reviewers validate, override, and own every decision that reaches a submission.
Speed without shortcuts
We compress the manual stages, not the standards. Faster reviews that still withstand regulatory and peer scrutiny.
Built by PharmaQuant.
ActiveTLR is built by PharmaQuant, a specialist evidence-generation and biostatistics group. The platform is shaped by people who run reviews for a living — systematic-review methodologists, information specialists, biostatisticians, and software engineers — so every automated step mirrors how a rigorous review is actually conducted.
- Hours, not weeks
- From clinical question to PRISMA-ready synthesis
- Every decision
- Logged with an auditable, inspectable rationale
- PICO · CoCoPop · PEO
- Evidence frameworks built in
See ActiveTLR on your own research question.
Book a walkthrough and watch a live review run from question to synthesis.
Get a demo